Chimerism in patients with AIHA
Twenty-six patients had chimerism checked between 1 month before AIHA
diagnosis to 1 year after diagnosis. Most patients (16/26; 61.5%) had
>95% total donor chimerism (full chimerism); 15.4% (4/26)
had chimerism between 50-94% donor (high mixed chimerism); 11.5%
(3/26) had 10-49% donor (low mixed chimerism); and 11.5% (3/26) had
<10% donor (no donor). Many patients (25/44, 75.8%) had at
least 1 peripheral blood chimerism observation within 30 days of their
AIHA diagnosis. Using the observation closest to AIHA diagnosis, 64%
(16/25) showed full chimerism, 24% (6/25) showed high mixed chimerism,
8% (2/25) showed low mixed chimerism, and 4% (1/25) showed no donor.