Patients
A retrospective study in adult patients who were either newly diagnosed with ITP or were under follow–up for chronic ITP at Yüzüncü Yil University Hospital, Van, Turkey was conducted from January 2010 to March 2019. Follow–up records and data of the patients in the hospital system were retrospectively evaluated. Inclusion criteria included; having a diagnosis of ITP, being older than 18 years, treatment indication and having undergone treatment for ITP, and for those with aH. pylori –positive test result, not having received eradication therapy. Patients who were younger than 18 years, were never treated for ITP, underwent eradication therapy, had missing data were excluded from the study.
The diagnosis of ITP was confirmed according to the Consensus Report on the Investigation and Management of Primary ITP (7). Patients were categorized into two groups: H. pylori –positive and –negative. Fecal antigen testing was used for the diagnosis of H. pyloriinfection in all patients. Demographic data of the patients at diagnosis, presence and severity of bleeding, initial platelet count, administered treatments, treatment response rates, and post–treatment platelet count were inspected.
The study was approved by the research ethics committee of Yuzuncu Yil University, Faculty of Medicine (date/reference number: 24.01.2018/002). All analyses were performed in accordance with the principles of the Declaration of Helsinki.