Patients
A retrospective study in adult patients who were either newly diagnosed
with ITP or were under follow–up for chronic ITP at Yüzüncü Yil
University Hospital, Van, Turkey was conducted from January 2010 to
March 2019. Follow–up records and data of the patients in the hospital
system were retrospectively evaluated. Inclusion criteria included;
having a diagnosis of ITP, being older than 18 years, treatment
indication and having undergone treatment for ITP, and for those with aH. pylori –positive test result, not having received eradication
therapy. Patients who were younger than 18 years, were never treated for
ITP, underwent eradication therapy, had missing data were excluded from
the study.
The diagnosis of ITP was confirmed according to the Consensus Report on
the Investigation and Management of Primary ITP (7). Patients were
categorized into two groups: H. pylori –positive and –negative.
Fecal antigen testing was used for the diagnosis of H. pyloriinfection in all patients. Demographic data of the patients at
diagnosis, presence and severity of bleeding, initial platelet count,
administered treatments, treatment response rates, and post–treatment
platelet count were inspected.
The study was approved by the research ethics committee of Yuzuncu Yil
University, Faculty of Medicine (date/reference number: 24.01.2018/002).
All analyses were performed in accordance with the principles of the
Declaration of Helsinki.