CONCLUSIONS
US-guided PLB in an outpatient setting has a low rate of complications and must keep been considered for selected individuals with indeterminate liver disease. The reason to perform it is undergoing a notable transition, where HCV chronic infection has been replaced by MAFLD. New strategies to prevent biopsy-related pain are still needed, especially for females.
Figure legends :
Figure 1 – Number of indications-related liver biopsies from 2015 to 2019 . AIH: autoimmune hepatitis; MAFLD: metabolic dysfunction-associated fatty liver disease.