WHAT THIS STUDY ADDS -
1. Combination medication of propofol with dexmedetomidine reduced the
EC50 of TCI propofol during gastrointestinal endoscopy
compared with administration of propofol without dexmedetomidine.
2. A 0.5-1 μg/kg dexmedetomidine caused a decrease in HR without
bradycardia. The decrease in dosage of propofol with increasing doses of
dexmedetomidine caused more stable MAP.
3. Dexmedetomidine is an ideal adjuvant drug to propofol during
gastrointestinal endoscopy.