WHAT IS ALREADY KNOWN ABOUT THIS SUBJECT -
1. Propofol is a popular drug for gastrointestinal endoscopy. However, Propofol may result in hypotension, bradycardia, and respiratory depression.
2. Dexmedetomidine, a α2 receptor agonist, provides analgesia and sedation but does not cause respiratory depression.
3. Co-administration could improve anaesthetic effectiveness and reduce the incidences of adverse events caused by a single drug.