Conclusions
Dexmedetomidine decreased the EC50 of TCI propofol
during gastrointestinal endoscopy. The decrease in dosage of propofol
with increasing doses of dexmedetomidine caused more stable MAP. A
0.5-1.0 μg/kg dexmedetomidine caused a decrease in heart rate without
bradycardia and did not cause prolonged recovery time. We believe
dexmedetomidine is an ideal adjuvant drug to propofol during
gastrointestinal endoscopy.