Conclusions
Dexmedetomidine decreased the EC50 of TCI propofol during gastrointestinal endoscopy. The decrease in dosage of propofol with increasing doses of dexmedetomidine caused more stable MAP. A 0.5-1.0 μg/kg dexmedetomidine caused a decrease in heart rate without bradycardia and did not cause prolonged recovery time. We believe dexmedetomidine is an ideal adjuvant drug to propofol during gastrointestinal endoscopy.