Title: Renal function is associated with one-month and one-year mortality in patients with intracerebral hemorrhage
Running title: eGFR and intracerebral hemorrhage
I-Kuan Wang, PhD 1, 2; Tzung-Hai Yen, PhD3,4; Chon-Haw Tsai, PhD 5; Yu Sun, PhD6; Wei-Lun Chang, MD7; Po-Lin Chen, MD8,9; Ta-Chang Lai MD10; Po-Yen Yeh, MD11; Cheng-Yu Wei, MD12; Cheng-Li Lin, MS13; Chi-Yuan Li, MD14, 15*; Fung-Chang Sung, PhD, MPH16,17*; Chung Y. Hsu, MD, PhD15, and Taiwan Stroke Registry Investigators
1Department of Internal Medicine, College of Medicine, China Medical University, Taichung, Taiwan
2Division of Nephrology, China Medical University Hospital, Taichung, Taiwan
3Division of Nephrology, Chang Gung Memorial Hospital, Taipei, Taiwan
4Chang Gung University College of Medicine, Taoyuan, Taiwan
5Department of Neurology, Show Chwan Memorial Hospital, Changhua County, Taiwan6Neurology, En Chu Kong Hospital, New Taipei City, Taiwan
7Department of Neurology, Show Chwan Memorial Hospital, Changhua County, Taiwan
6Department of Neurology, College of Medicine, National Cheng Kung University, Tainan, Taiwan
8Neurological Institute, Taichung Veterans General Hospital, Taichung, Taiwan9Department of Neurology, School of Medicine, National Yang-Ming University, Taipei, Taiwan.10Division of Neurology Department of Internal medicine, Cheng Hsin General Hospital, Taipei, Taiwan11Department of Neurology, St. Martin De Porres Hospital, Chiayi , Taiwan12Department of Neurology, Chang Bing Show Chwan Memorial Hospital, Changhua, Taiwan
13Management Office for Health Data, China Medical University Hospital, Taichung, Taiwan
14Department of Anesthesiology, China Medical University Hospital, Taichung, Taiwan
15Graduate Institute of Biomedical Science, China Medical University College of Medicine, Taichung, Taiwan
16Department of Health Services Administration, China Medical University College of Public Health, Taichung 404, Taiwan
17Department of Food Nutrition and Health Biotechnology, Asia University, Taichung 413, Taiwan
Corresponding author:
Fung-Chang Sung, PhD, MPH
Professor
Department of Health Services Administration, China Medical University College of Public Health, Taichung 404, Taiwan
91 Hsueh Shih Road
Taichung 404, Taiwan
Tel: 886-4-2205-4070
Fax: 886-4-2201-9901
E-mail: fcsung1008@yahoo.com
*Equal distribution
Word count: 201 words in the Abstract, 1981 words in the text; 3 tables, 3 figures, and 26 references, 2 supplementary tables
Acknowledgements : This work is supported in part by Ministry of Health and Welfare, Taiwan (MOHW109-TDU-B-212-114004), Children’s Hospital of China Medical University (DMR-108-045), China Medical University Hospital (DMR-110-037 and DMR-109-175), Academia Sinica Stroke Biosignature Project (BM10701010021), MOST Clinical Trial Consortium for Stroke (MOST 107-2321-B-039 -004), Tseng-Lien Lin Foundation, Taichung, Taiwan, and Katsuzo and Kiyo Aoshima Memorial Funds, Japan.
Author Contributors: I-Kuan Wang, Tzung-Hai Yen, Chon-Haw Tsai, Yu Sun, Wei-Lun Chang, Po-Lin Chen, Ta-Chang Lai, Po-Yen Yeh, Cheng-Yu Wei designed the study and drafted the manuscript. Cheng-Li Lin conducted the statistical analysis. Chi-Yuan Li, Chung Y. Hsu, and Fung-Chang Sung revised the manuscript.
Key words: estimated glomerular filtration rate, intracerebral hemorrhage, mortality, predictor, renal function
Title: Renal function is associated with one-month and one-year mortality in patients with intracerebral hemorrhage