Title: Renal function is associated with one-month and one-year
mortality in patients with intracerebral hemorrhage
Running title: eGFR and intracerebral hemorrhage
I-Kuan Wang, PhD 1, 2; Tzung-Hai Yen,
PhD3,4; Chon-Haw Tsai, PhD 5; Yu
Sun, PhD6; Wei-Lun Chang, MD7;
Po-Lin Chen, MD8,9; Ta-Chang Lai
MD10; Po-Yen Yeh, MD11; Cheng-Yu
Wei, MD12; Cheng-Li Lin, MS13;
Chi-Yuan Li, MD14, 15*; Fung-Chang Sung, PhD,
MPH16,17*; Chung Y. Hsu, MD, PhD15,
and Taiwan Stroke Registry Investigators
1Department of Internal Medicine, College of Medicine,
China Medical University, Taichung, Taiwan
2Division of Nephrology, China Medical University
Hospital, Taichung, Taiwan
3Division of Nephrology, Chang Gung Memorial Hospital,
Taipei, Taiwan
4Chang Gung University College of Medicine, Taoyuan,
Taiwan
5Department of Neurology, Show Chwan Memorial
Hospital, Changhua County, Taiwan6Neurology, En Chu Kong Hospital, New Taipei City,
Taiwan
7Department of Neurology, Show Chwan Memorial
Hospital, Changhua County, Taiwan
6Department of Neurology, College of Medicine,
National Cheng Kung University, Tainan, Taiwan
8Neurological Institute, Taichung Veterans General
Hospital, Taichung, Taiwan9Department of Neurology, School of Medicine, National
Yang-Ming University, Taipei, Taiwan.10Division of Neurology Department of Internal
medicine, Cheng Hsin General Hospital, Taipei, Taiwan11Department of Neurology, St. Martin De Porres
Hospital, Chiayi , Taiwan12Department of Neurology, Chang Bing Show Chwan
Memorial Hospital, Changhua, Taiwan
13Management Office for Health Data, China Medical
University Hospital, Taichung, Taiwan
14Department of Anesthesiology, China Medical
University Hospital, Taichung, Taiwan
15Graduate Institute of Biomedical Science, China
Medical University College of Medicine, Taichung, Taiwan
16Department of Health Services Administration, China
Medical University College of Public Health, Taichung 404, Taiwan
17Department of Food Nutrition and Health
Biotechnology, Asia University, Taichung 413, Taiwan
Corresponding author:
Fung-Chang Sung, PhD, MPH
Professor
Department of Health Services Administration, China Medical University
College of Public Health, Taichung 404, Taiwan
91 Hsueh Shih Road
Taichung 404, Taiwan
Tel: 886-4-2205-4070
Fax: 886-4-2201-9901
E-mail: fcsung1008@yahoo.com
*Equal distribution
Word count: 201 words in the Abstract, 1981 words in the text; 3 tables,
3 figures, and 26 references, 2 supplementary tables
Acknowledgements : This work is supported in part by Ministry of
Health and Welfare, Taiwan (MOHW109-TDU-B-212-114004), Children’s
Hospital of China Medical University (DMR-108-045), China Medical
University Hospital (DMR-110-037 and DMR-109-175), Academia Sinica
Stroke Biosignature Project (BM10701010021), MOST Clinical Trial
Consortium for Stroke (MOST 107-2321-B-039 -004), Tseng-Lien Lin
Foundation, Taichung, Taiwan, and Katsuzo and Kiyo Aoshima Memorial
Funds, Japan.
Author Contributors: I-Kuan Wang, Tzung-Hai Yen, Chon-Haw Tsai,
Yu Sun, Wei-Lun Chang, Po-Lin Chen, Ta-Chang Lai, Po-Yen Yeh, Cheng-Yu
Wei designed the study and drafted the manuscript. Cheng-Li Lin
conducted the statistical analysis. Chi-Yuan Li, Chung Y. Hsu, and
Fung-Chang Sung revised the manuscript.
Key words: estimated glomerular filtration rate, intracerebral
hemorrhage, mortality, predictor, renal function
Title: Renal function is associated with one-month and one-year
mortality in patients with intracerebral hemorrhage