Study design and Sample
We conducted a cross-sectional study to construct the CPMs of sever CRF.
The first 70% CC case data were included in the model building group
(training set=196), and the last 30% CC case data were included in the
validation group (validation set=88), including 284 people. The
intervention study was designed as a randomized controlled trial. The
subjects were randomly assigned to the experimental group (N=40) and the
control group (N=38) at a ratio of 1:1 (Figure 1). The control group
received routine care, while the experimental group received online
8-week MBSR (Table 1) on the basis of routine care, and patients were
followed up for 3 and 6 months.
The samples of this study were all CC patients from a tertiary hospital
in Shenyang. According to the sample size, the researchers continuously
collected CC patients who met the standards and completed the
questionnaire survey. The inclusion criteria were: (1) patients with
primary CC confirmed by pathology; (2) aged over 18; (3) communicate
independently and fill in questionnaires; (4) know the illness of
themselves; (5) volunteer to participate in the investigation and sign
the informed consent. Exclusion criteria for study subjects: (1)
patients with other malignant tumors at the same time; (2) patients with
a history of psychiatric diseases or mental retardation; (3) patients
who have received psychotherapy or intervention within one year.
Rejection criteria of study objects: (1) no outcome indicators of
patients were measured at any two time points. The abscission criteria
of the subjects: (1) voluntary withdrawal from the study; (2)
interruption of treatment or death.