Limitations
The major limitation of this study was the small sample size and short time course, further compounded by the self-selecting group of patients who completed all study time points and did not withdraw. Additionally, this sample was composed primarily of white males, which impacts the generalizability of all of the results. We aimed to enroll an equal and diverse population, but given the exclusion criteria, diversity both in race and sex as well as medical comorbidities was not well-reflected in this small sample size.