Table 1: Baseline characteristics of the 634 first trimester
pregnant women recruited for NAFLD assessment
Though the diagnosis of diabetes mellitus reported by only 6 women, 18
(including the 6 with DM) reported history of hyperglycemia detected
once or more than once. Prevalence of hypertension (36, 5.9%),
dyslipidemias (8, 1.3%), hypothyroidism (17, 2.7%) was low. Of the
multigravida women, history of GDM was reported by 17 (2.7%) and the
history of having at least one miscarriage was 19.1% (n=121).
Of the pregnant women recruited, 324 (51.2%) had either grade I fatty
liver (FLG I) (n=234, 37.0%, 95% CI 33.2% - 40.9%) or grade II fatty
liver (FLG II) (90, 14.2%, 95% CI 11.6% - 17.2%). None of the
participants had fatty liver grade III (FLG III).
The prevalence of fatty liver in the non-pregnant group was 51.7%, with
grade II and grade I prevalence of 14.2% (n 21) and 37.0%(n 4),
respectively. There was no statistically significant difference between
the two groups.
All tested liver parameters, biophysical parameters and OGTT
2nd hour values gradually increased across the fatty
liver grades. The difference between fatty liver grades I and II was
higher than the difference between grades 0 and I in all parameters
except the FBS value, minimum DBP, portal vein diameter and dome-to-pole
length. FBS in the first trimester was reduced gradually across the
fatty liver grades (Table 2).