Renal functions of nonpregnant women of reproductive age
Data from 2,012 nonpregnant women of reproductive age were available for the comparison group. The mean (SD) age of this group was 35.9 (8.2) years. The mean (SD) sCr of the group was 62.8 (12.4) μmol/L with a 97.5th percentile of 89.0 μmol/L. The mean (SD) eGFR was 105.1 (27.9) mL/min/1.73 m2 with a median of 100.8 (IQR 85.5-118.4) mL/min/1.73 m2. The distribution of sCr and eGFR showed that the sCr values were fairly normally distributed (skewness of 0.182), while eGFR was skewed to the right (skewness of 1.21). However, the Kolmogorov-Smirnov statistics showed a violation of normality for both parameters (p<0.001). Age-disaggregated mean sCr and eGFR values were compared to identify homogenous subsets of age groups using one-way ANOVA. Based on the ANOVA results, two subgroups for sCr and three subgroups for eGFR were identified (Table 1). Although the mean sCr was significantly different, the 95th percentile for sCr was almost similar.