No switching IS drugs group Switching IS drugs group P value
Number 1687 345
Death 139 (8.2) 11 (3.2) 0.005
Viral infection status (positive)
EBV 911 (54.0) 182 (52.8) 0.716
CMV 463 (27.4) 112 (32.5) 0.069
HBV 91 (5.4) 13 (3.8) 0.265
Acute rejection in 3 months after LT 385 (22.8) 171 (49.6) <0.001
Vascular Complications
Portal vein 88 (5.2) 8 (2.3) 0.03
Hepatic artery 31 (1.8) 3 (0.9) 0.295
Respiratory complications 455 (27.0) 87 (25.2) 0.546
Digestive complications 366 (21.7) 58 (16.8) 0.257
Urinary complications 98 (5.8) 31 (9.0) 0.037
Mental and neurological complications 33 (2.0) 16 (4.6) 0.006
Hematological complications 189 (11.2) 47 (13.6) 0.236
Skeletal complications 38 (2.3) 7 (2.0) 0.955
Allergy or urticaria 398 (23.6) 65 (18.8) 0.065
PTLD 84 (5.0) 8 (2.3) 0.043