CONCLUSION
Hemochromatosis can be detected incidentally by routine examination and blood analysis, and its diagnosis can be made easily by mutation analysis. Today, C282Y and H63D mutations are detected in whole blood by polymerase chain reaction (PCR). Accumulation of iron in the body and detection of homozygous C282Y mutation is sufficient for the diagnosis of the disease. C282Y homozygosity  is the most common mutation for hemochromatosis and proceeds with maximum iron accumulation. While the patients with both C282Y/H63D heterozygosity  show moderate iron accumulation, H63D homozygotes , and C282Y heterozygotes  are usually normal.