Introduction:
Tourette’s syndrome (TS) is a chronic developmental neuropsychiatric
disorder with an onset in early childhood, affected by both genetic and
environmental factors. TS is characterized by multiple complex motor and
vocal tics, in addition to some other psychological disorder such as
attention deficit hyperactivity disorder (ADHD) and
obsessive–compulsive disorder (OCD). The exact pathophysiology of TS is
unclear but recent studies suggest that there may be a defect in the
Cortico-Striato-Thalamo-Cortical (CSTC) circuit. Besides self-limited
cases, some of TS patients with mild symptoms may need conventional
treatments such as psycho-behavioral therapy, educational therapy and
pharmacotherapy while refractory cases are potential candidates for deep
brain stimulation (DBS) procedure which leads to an improvement in both
tic component and other comorbidities of TS, but with different extents
[1]. Herein we report a patient with TS which his OCD improved after
DBS without his tic to be improved.