Study population
100 patients with organ failure in Jiangning Hospital of Nanjing Medical University from September 2020 to March 2021 were randomly selected, including 60 males and 40 females, with an average age of 69.08±16.68 years. In addition, 30 healthy subjects (blood routine, urine routine, liver and kidney function, heart color ultrasound, blood glucose and other examinations were normal) were selected as the normal control group, including 14 males and 16 females, with an average age of 60.23±13.99 years old. This study was approved by the Ethics Committee of Jiangning Hospital Affiliated to Nanjing Medical University.