Conclusion:
The histomorphology and the immunohistochemical study of the
neuroendocrine markers are the basis for the definitive diagnosis of
invasive breast carcinoma with neuroendocrine differentiation. But the
combined approach with clinical assessment and radiological images aid
in the diagnosis. The current diagnostic methods and treatment protocols
are similar to other invasive breast carcinomas. Because it has a poorer
prognosis than invasive carcinoma of the breast without neuroendocrine
tumors, it is important to make the early diagnosis of the
neuroendocrine component. Hence, larger studies are needed to better
understand the biological features of invasive breast carcinoma with
neuroendocrine differentiation.