Efficacy outcomes
75% (15/20) and 60% (12/20) of participants achieved desensitization
and 8-week SU respectively. Amongst those who completed treatment and
had a DBPCFC outcome, 94% (15/16) achieved desensitization and 75%
(12/16) achieved SU. Of the 12 participants with SU at the
end-of-treatment (T3), 10 underwent DBPCFC at 3-years post-treatment
(T5) following an 8-week period of peanut elimination; 6 had persistent
SU. Of the 2 participants with SU at T3 who did not undergo the T5
DBPCFC, 1 was lost to follow-up and 1 failed an optional peanut DBPCFC
at T4 (12-months post-treatment) and was ineligible for the 3-year
post-treatment DBPCFC. The overall rate of persistent SU amongst initial
treatment responders was therefore 54.5% (6/11).