RITA VS RA as second arterial conduit
Baseline characteristics of patients in the unmatched and matched cohort
are presented in Table-4. In the unmatched cohort, patients in the RA
group were more likely to be female and obese and to have diabetes,
hyperlipidemia and moderate renal impairment. Whereas patients in the
RITA group were more likely to be operated on as an emergency or urgent
cases and to have arterial hypertension and left main stem disease.
After PS-matching, both groups were comparable for all baseline
characteristics(Table-4). PS-matching selected 174-pairs and both groups
showed good degree of balance.
The mean number of grafts performed and the rate of OPCAB in the RITA
group was higher than in the RA group before as well as after PS
matching. In the unmatched cohort, the prevalence of IR in the RA group
was higher than in RITA group(33.8% vs 22.7%,p=0.0029). However after
matching, no difference in terms of incomplete revascularization was
observed between both groups(Table-4).
Before as well as after PS-matching, no significant differences were
observed between both groups in terms of 30-day mortality, 30-day MACCE,
reoperation for bleeding and incidence of DSWI(Table-5).
In the unmatched cohort, survival at-5,-10 and 14-years were 92.6% vs
93.0%, 82.2% vs 77.4% and 75.4% vs 70.8% in the RITA group vs RA
group, respectively(Log-rank p=0.27)(Figure.3A). In the matched cohort,
Survival at 5, 10 and 14-years were 93.2% vs 93.3%, 77.7% vs 77.8%
and 69.6% vs 72.0% in the RITA group vs RA group,
respectively(Log-rank p=0.88)(Figure.3B). RA and RITA as second arterial
conduit had comparable long-term mortality
before(HR:1.22;95%CI;0.82-1.82;p=0.3) as well as after
PS-matching(HR:0.96;95%CI;0.58-1.58;p=0.87).
Multivariable analysis identified Age>70, diabetes, severe
renal impairment, PVD and impaired LV function as independent predictors
of late mortality in patients with 2nd-arterial
conduit(Table-3).