Data are expressed as mean±SD or n(%). Moderate and severe renal impairment defined as eGFR>50<85ml/min/1.73m2 and eGFR<50ml/min/1.73m2,respectively. BMI=Body mass index;CAE=Cerebral adverse events;CLD=Chronic lung disease;LM=Left main disease;EF=Ejection fraction;MI=Myocardial Infarction;NYHA=New York Heart Association;OPCAB=Off-pump coronary artery bypass grafting;PCI=Percutaneous coronary intervention;PVD=Peripheral vascular disease.