Consecutive inpatients and medical personnel with suspected COVID-19 were included in a prospective cross-sectional study in a real-life clinical setting (n=3’658). A positive RT-PCR from a nasopharyngeal swab was defined as the primary reference standard test representing a “previous SARS-CoV-2” infection (COVID-19). Abbreviations: ELISA, enzyme-linked immunosorbent assay; ECLIA, electrochemiluminescence immunoassay; CLIA, chemiluminescence immunoassay; LFI, lateral flow immunoassay; N, nucleoprotein; RBD, receptor binding domain of the SARS-CoV-2 spike glycoprotein; S1/2, domain 1 or 2 of the SARS-CoV-2 spike glycoprotein; RBD+, extended receptor binding domain of the SARS-CoV-2 spike glycoprotein
Table 3: Diagnostic accuracy of serological immunoassays for the presence of neutralizing antibodies.