Sarcoidosis and renal cell carcinoma: a very rare association
Hela Jebali1,4, Meriam Khadhar2,3,4, Ikram Mami1,4, Fethi Ben Hmida3,4 , Lamia Rais1,4 Lilia Ben Fatma1,4Mohamed Karim Zouaghi1,4,Alya zhini5, slim haout5
1.Department of Nephrology La Rabta Hospital, Tunis – Tunisia.
2.1Department of Nephrology Mongi slim Hospital, Tunis – Tunisia.
3.Laboratory of Kidney Pathology (LR00SP01) Charles Nicolle Hospital. Tunis - Tunisia
4.Faculty of Medicine, University of Tunis El Manar, Tunis, Tunisia.
5. Department of pathological anatomy La Rabta Hospital, Tunis – Tunisia.
Granulomatosis can be observed in cancer patients. Granulomatosis reaction associated with tumor has been designated as sarcoid-like reaction. On the other side, very few cases of association of systemic sarcoidosis and neoplasia have been reported. Herein, we reported two cases of sarcoidosis and renal cell carcinoma. In the first case, carcinoma revealed sarcoidosis and in the second case, management of renal sarcoidosis revealed a silent renal cell carcinoma. The two cases highlight the relationship between sarcoidosis and renal cancer.
Keywords : granuloma, sarcoidosis, sarcoid-like reaction, renal cell carcinoma