Multivariate model
Multivariate regression models were generated for both of the novel parameters (CoV ≥ 0.7 and VE < 50) and included age, gender, LVEF, and VE burden. The two novel parameters were not included in the same model due to the risk of multicollinearity. The novel prediction parameters both remained significant in multivariate models. For CoV the R2 value was 0.79 (SE 0.34) with both higher LVEF (p=0.04) and CoV ≥ 0.7 (p=0.01) predictors of a RVOT SOO. For VE < 50 in any hour, the R2 value was 0.88 (SE 0.22) and < 50 VE was the only variate that significantly predicted a RVOT SOO (p = 0.006). The total VE burden did not emerge as an independent predictor of SOO.