Results of the search
The flow chart of the study is presented in Figure S1. After rejecting
articles not associated with the research question, 11 articles were
included in the search for studies describing pregnancy outcomes after
attempting natural conception in recurrent miscarriage couples from 96
publications, and 2 articles were included in the search for studies
reporting on reproductive outcomes after EM or PGD in RPL carriers.
Eleven comparative studies (including PS Zheng 2021, our pending
published data) compared the first and/or accumulated pregnancy outcomes
of carriers to the pregnancy outcomes of noncarriers after attempting
natural conception[8-17]. Two comparative studies compared the
pregnancy outcomes of carriers after attempting EM or PGD[18, 19].
The population characteristics of the 13 included studies are shown in
the Table 1.