1 | INTRODUCTION
A comprehensive survey of deep coral reefs in the high seas showed that
policymakers should give more attention to protection of ocean
ecosystems and marine mammals [1, 2]. Due to a linkage with sources
of sustainable food, energy, materials, biomedicine, and many others, it
should be a priority attention from the United Nations for the future of
this global ecosystem [3]. Currently, ocean economy is accelerating
development in the globe and has become a vital support for human
sustainable development. As important biomedical resources, drugs from
marine organisms have long been used and exhibit unique advantages in
clinical practices. Hence, it is a great task to protect and develop
ocean resources and prevent and control ocean pollution since some
marine compounds are also valuable tools in biomedicine and clinical
applications [4, 5].
Major marine natural products (MNPs) and organisms include sea urchin,
sea squirts or ascidians, sea cucumbers, sea snake, sponge, soft coral,
marine algae, and microalgae. As vital biomedical resources for the
discovery of marine drugs, bioactive molecules, and agents for treatment
of infectious diseases and major non-communicable diseases (mNCDs), MNPs
have many bioactive potentials. This article discusses the studies of
MNPs as huge, novel, and promising biomedical resources for
anti-infection of coronavirus (SARS-CoV-2 and its variants) and related
cardiovascular disease (irCVD) as well as possible mechanisms linked to
human immunity.