Chijian Zhang1,2, Shubhang Sharma1, Chengwei Ma1, and An-Ping Zeng1
aInstitute of Bioprocess and Biosystems Engineering, Hamburg University of Technology, Hamburg, Germany
bHua An Tang Biotech Group Co., Ltd, Guangzhou, China
Correspondence: Prof. An-Ping Zeng (aze@tuhh.de), Institute of Bioprocess and Biosystems Engineering, Hamburg University of Technology, Denickestr.15, D-21071, Hamburg, Germany
Abbreviations: PDO, 1,3-Propanediol; HPLC, high performance liquid chromatography; ALE, adaptive laboratory evolution; MA, methyl acetate; MB, methyl butyrate; DSP, downstream processing