Statistical analysis
All data were summarized using standard descriptive statistical methods.
Prevalence values were reported with corresponding exact binomial 95%
confidence intervals (CI). Comparisons of qualitative variables between
patient groups were completed using chi-square tests, and comparisons
between quantitative variables between patient groups were completed
using either t-tests or, in the case of non-normality, Mann-Whitney U
tests. The comparison of SBP and DBP indices at diagnosis and 1-month
post-diagnosis was completed using paired t-tests. Logistic regression
models were used to assess risk factors for the occurrence of AKI, CKD,
and HTN. Variables assessed included age at diagnosis, gender, ALL risk
category, number of nephrotoxic agents, number of hospitalizations, need
for vasopressors, need for radiation, obesity, current steroid use,
history of AKI. All analyses were performed using SAS software, version
9.4 (SAS Institute, Cary, NC).