Risks of stroke
Table 2 presents the aHRs of stroke after adjusting for covariates. Stroke risk was significantly higher in the pre-eclampsia/eclampsia group than in the non-pre-eclampsia/eclampsia group (aHR = 2.05, 95% CI =1.67-2.52, p < 0.001).
Women with old delivery age had higher risk of stroke than that of women with young delivery age (Table 2), with highest risk being 2.61 (p < 0.001) for age >35 years, compared to women with age at delivery <30 years.
From the Cox regression analysis results presented in Table 3, delivery-related variables, such as cesarean section, multiple gestation, hospital level, and the season of maternal delivery did not have significant risk for stroke.
For comorbidities, Hypertension increased risks for stroke with aHR 3.35 (95% CI = 1.99-5.63, p <0.001) in these two matched cohorts. APH had a significant risk for stroke. Other comorbidities such as GDM, anemia, and PPH had no significant impact on stroke occurrence.
Socioeconomic variables, such as geographic region and urbanization level, had no significant stroke risk except family income. Women in median or high-income families had a higher risk of stroke than that of women in low-income families.