Acknowledgements
The authors are grateful to Prof. Mikhail Panteleev (CTP PCP RAS) and Ms. Daria Morozova (Pirogov RNRMU) for valuable discussions on the subject. The authors want to thank Ms. Antonina Petlenko (CTP PCP RAS) and Ms. Evgenia Ponomarenko (NMRC PHOI) for the technical assistance during experiments. The study was supported by Russian Presidential Scholarship SP-2675.2019.4 for AAM and Russian Presidential Grants МК-432.2020.7 (for EMK) and MK-6271.2021.1.4 (for NAP); a grant from the endowment foundation ”Science for Children” (for AAM and ANS) and Lomonosov Moscow State University Digital Medicine School. JAE is financially supported by the Interdisciplinary Center for Clinical Research (IZKF) Münster (grant: IZKF: Ebl-A/009/21). .