Conclusions
After AF ablation, there is a significant asymmetrical reduction of the LAA ostial area that was independent of LVEF and LAEF changes. LAA ostial area was larger in patients with HFrEF, and in patients with “cauliflower” LAA morphology. Larger LAA ostial area was associated with greater LA and LAA volume, and with lower LAEF and LA strain. Remodeling of the LAA after AF ablation may help account for reduced risk of stroke and increased cardiac function. Future studies are needed to elucidate underlying mechanisms and explore clinical implications.