CONCLUSION
Only the beginning of the cell biology and molecular genetics is being
understood and 60% of the genetic basis of ARS in still unknown. Early
diagnose is important due to initiate early treatment hereby reduce the
possible effect of the anterior chamber changes and postpone or
hopefully avoid blindness. Because of the high incidence of glaucoma, it
is crucial to follow the patients frequently and monitor the intraocular
pressure and the appearance of the optic nerve. Likewise, it is
important to initiate early treatment of dental and facial abnormalities
to improve functional and aesthetic outcome. As the care of the patients
is complex it is advisable to have highly specialized multidisciplinary
team to diagnose and treat this patient group.