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\begin{document}

\title{Clinical Presentation and Outcomes of Hospitalized Children with
Covid-19 in Mexico City}



\author[1]{David Diaz}%
\author[2]{Samuel Urrutia}%
\author[3]{Gabriel Gutierrez}%
\author[3]{Francisco Cuevas}%
\affil[1]{Instituto Nacional de Pediatría}%
\affil[2]{The University of Texas MD Anderson Cancer Center}%
\affil[3]{Instituto Nacional de Pediatria}%


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  \date{May 20, 2024}


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\begin{abstract}
Background. COVID-19 is usually less severe and has lower case fatality
in children than in adults. We aimed to characterize the clinical and
radiological features of children and adolescents hospitalized with
laboratory-confirmed SARS-CoV-2 infection and to evaluate the risk
factors for COVID-19-related severity in the pediatric Mexican
population. Methods. We did an analysis of all patients younger than 18
years who had quantitative RT-PCR-confirmed COVID-19, admitted to the
National Pediatrics Institute, and described their clinical
characteristics with the radiological findings at admission, related to
the severity and clinical outcome. Results. A total of 129 patients had
available data showing laboratory-confirmed SARS-CoV-2 infection and
were included in the sample. Among these patients the most common signs
were fever (82.2\%), tachypnea (72.1\%) and cough (71.3\%). The most
frequent radiological pattern that stood out was the interstitial
pattern (66.7\%). History of oncologic pathology (25.6\%) was the most
frequent past medical history. ESR was the only laboratory value
significantly associated with severity (27.82 ? 23.83 mm/hr). NSAIDs
(93\%), antibiotics (57.4\%), and steroids (40.3\%) were the most common
medication given. The average hospitalization stay was 14.2 days, 21.7\%
of the total patients required transfer to the intensive care unit. At
discharge, 20.2\% required oxygen on an outpatient basis, and
unfortunately 7.0\% of the patients who were admitted to the institute
for COVID-19 died. Conclusions. COVID-19 in children was associated with
mild symptoms and good prognosis; ESR was the only laboratory value
significantly associated with severity. Patients with
hematologic/oncologic co-morbidities had severe presentations.%
\end{abstract}%



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