1 Top 10 pedigrees of stillbirth high-risk pedigrees (n=390) of stillbirth cases (n=2498) sorted by their FSIR p-values, FSIR values and founders to eliminate any multiple founders claiming the same descendants through marriage.
2Birth/death year of the founder
3Familial Standardized Incidence Ratio, comparing the incidence of stillbirth in a family to its expected incidence in the population
4The observed and expected counts of stillbirth between pedigrees may overlap
Figure 1 . A pedigree (pedigree 3 in Table 1; FSIR=6.32 [p-value<0.001]) showing 10 stillbirth cases indicated in black shades. Gray circles indicate study eligible mothers. The small triangle denotes the founder. Pedigree trimmed to demonstrate the affected lineages.