1 Top 10 pedigrees of stillbirth high-risk pedigrees
(n=390) of stillbirth cases (n=2498) sorted by their FSIR p-values, FSIR
values and founders to eliminate any multiple founders claiming the same
descendants through marriage.
2Birth/death year of the founder
3Familial Standardized Incidence Ratio, comparing the
incidence of stillbirth in a family to its expected incidence in the
population
4The observed and expected counts of stillbirth
between pedigrees may overlap
Figure 1 . A pedigree (pedigree 3 in Table 1; FSIR=6.32
[p-value<0.001]) showing 10 stillbirth cases indicated in
black shades. Gray circles indicate study eligible mothers. The small
triangle denotes the founder. Pedigree trimmed to demonstrate the
affected lineages.