Short summary:
A unique CD27-IgD- B-cells population was found to be significantly higher in number and proportion in the sputum of severe eosinophilic asthma, particularly the oral corticosteroid-dependent subgroup and might be related to a local autoimmunity phenomenon.
Key words : severe asthma, B-cells, airway autoimmunity, autoantibodies
Word count :645 ; Table :0; Figures :2;References : 6
Online supplementary: 3 tables, 1 figure