Figure 3. Isorhamnetin alleviated AngII-induced abnormal
diastolic Ca2+ loading in HL-1 cells.
(A) Representative confocal line scan images showing
Ca2+ waves in HL-1 cells from three groups. Red arrows
show abnormal Ca2+ wave. (B) Representative
fluorescence intensity. Quantification of Ca2+diastolic [Ca2+]: (C) amplitude; (D) time to peak;
(E) decay time; (F) wave frequency in 30 s. (G) The frequency of
abnormal Ca2+ wave from three groups (control, n = 6;
AngII, n = 7; AngII+isorhamnetin, n = 6). **P < 0.01
control vs. AngII by one-way ANOVA with post-hoc test (Tukey);##P < 0.01 AngII vs.
AngII+isorhamnetin; #P < 0.05 AngII
vs. AngII+isorhamnetin by one-way ANOVA with post-hoc test
(Tukey).