Figure 3. Isorhamnetin alleviated AngII-induced abnormal diastolic Ca2+ loading in HL-1 cells.
(A) Representative confocal line scan images showing Ca2+ waves in HL-1 cells from three groups. Red arrows show abnormal Ca2+ wave. (B) Representative fluorescence intensity. Quantification of Ca2+diastolic [Ca2+]: (C) amplitude; (D) time to peak; (E) decay time; (F) wave frequency in 30 s. (G) The frequency of abnormal Ca2+ wave from three groups (control, n = 6; AngII, n = 7; AngII+isorhamnetin, n = 6). **P < 0.01 control vs. AngII by one-way ANOVA with post-hoc test (Tukey);##P < 0.01 AngII vs. AngII+isorhamnetin; #P < 0.05 AngII vs. AngII+isorhamnetin by one-way ANOVA with post-hoc test (Tukey).