Author contribution statement
K.A., D.X., N.M., and H.I. designed the study. K.A., D.X., Y.O., Z.Y., S.L., Y.M., and K.T. participated in the data acquisition and analysis. K.T. and K.A. synthesized the isorhamnetin for the experiments. H.I., K.T., A.N., M.I., and K.A. supervised this study. K.A. and D.X. drafted the manuscript. H.I., K.T., K.A., and N.M. revised the manuscript for intellectual content.