Author contributions
Z.H, G.L, H.L, G.Q.C contributed to the overall design of the PhASE system. Z.H, L.S, G.L, Z.Z, S.F, J.G, C.C, C.Q contributed to molecular cloning; Z.H, L.S, G.L, H.L collected and analyzed imaging data together; Z.H, L.S, J.G and X.W tested the application of PhASE system on metabolic reactions and analyzed the data. Z.H drafted the article and figures, which were revised by X.W and G.Q.C. Under the approval of X.W and G.Q.C, the article was submitted to scientific journals.