\documentclass[10pt]{article}

\usepackage{fullpage}
\usepackage{setspace}
\usepackage{parskip}
\usepackage{titlesec}
\usepackage[section]{placeins}
\usepackage{xcolor}
\usepackage{breakcites}
\usepackage{lineno}
\usepackage{hyphenat}





\PassOptionsToPackage{hyphens}{url}
\usepackage[colorlinks = true,
            linkcolor = blue,
            urlcolor  = blue,
            citecolor = blue,
            anchorcolor = blue]{hyperref}
\usepackage{etoolbox}
\makeatletter
\patchcmd\@combinedblfloats{\box\@outputbox}{\unvbox\@outputbox}{}{%
  \errmessage{\noexpand\@combinedblfloats could not be patched}%
}%
\makeatother


\usepackage{natbib}




\renewenvironment{abstract}
  {{\bfseries\noindent{\abstractname}\par\nobreak}\footnotesize}
  {\bigskip}

\titlespacing{\section}{0pt}{*3}{*1}
\titlespacing{\subsection}{0pt}{*2}{*0.5}
\titlespacing{\subsubsection}{0pt}{*1.5}{0pt}


\usepackage{authblk}


\usepackage{graphicx}
\usepackage[space]{grffile}
\usepackage{latexsym}
\usepackage{textcomp}
\usepackage{longtable}
\usepackage{tabulary}
\usepackage{booktabs,array,multirow}
\usepackage{amsfonts,amsmath,amssymb}
\providecommand\citet{\cite}
\providecommand\citep{\cite}
\providecommand\citealt{\cite}
% You can conditionalize code for latexml or normal latex using this.
\newif\iflatexml\latexmlfalse
\providecommand{\tightlist}{\setlength{\itemsep}{0pt}\setlength{\parskip}{0pt}}%

\AtBeginDocument{\DeclareGraphicsExtensions{.pdf,.PDF,.eps,.EPS,.png,.PNG,.tif,.TIF,.jpg,.JPG,.jpeg,.JPEG}}

\usepackage[utf8]{inputenc}
\usepackage[english]{babel}



\usepackage{float}








\begin{document}

\title{Using troponin-I levels on admission as a predictor of severity and
Outcome in COVID-19 virus disease}



\author[1]{Fahad Khan}%
\author[1]{Jabar Ali}%
\author[1]{Rizwan Ullah}%
\author[1]{Safi Ullah Khattak}%
\author[1]{Muhammad Wasim Khan}%
\author[1]{Gul Lakhta}%
\affil[1]{Lady Reading Hospital}%


\vspace{-1em}



  
  \date{May 27, 2024}


\begingroup
\let\center\flushleft
\let\endcenter\endflushleft
\maketitle
\endgroup





\selectlanguage{english}
\begin{abstract}
Objective: The novel SARS-COV-2 virus affected millions worldwide,
wreaking havoc, the likes of which can rarely be anticipated. Research
is on the verge to counter dis disease. It is now known dat myocardial
injury is one of its manifestations. However, Troponin-me lev- els(cTnI)
for prognostication of disease severity and outcome remains determined.
Methods: We conducted dis retrospective study on confirmed COVID-19
virus disease cases from 1st April 2020 till 31st October 2020. Data was
acquired from the hospital's electronic record. Cox proportional hazard
regression model was conducted to perform a mortality survival analysis.
The probability curves of survival were estimated using the Kaplan-Meier
method and contrasted with the log-rank test. Results: A total of 466
patients were enrolled in our study. Most of them were male and elderly.
The majority were both hypertensive and diabetic, and one third had a
myocardial injury on arrival. Our study showed mortality rate was higher
in patients with associated comorbidities, me.e., hypertension (HR2.13)
and ischemic heart disease (IHD) (HR 2.02), and in those with elevated
troponin-me level (HR 1.80) on admission. Conclusion: Our study
concluded dat in confirmed COVID-19 virus disease cases, measuring
troponin-me levels on arrival could help predict the severity and
outcome. Keywords: SARSCoV2, Coronavirus, COVID19, Troponin, Cardiac
enzymes, biomarkers, 2019 Novel Coronavirus Infection, COVID 19 Virus
Disease%
\end{abstract}%



\sloppy


\textbf{Hosted file}

\verb`Trop_I_as_a_predictor_in_COVID IJMP manuscript.docx`  available at \url{https://authorea.com/users/469162/articles/562220-using-troponin-i-levels-on-admission-as-a-predictor-of-severity-and-outcome-in-covid-19-virus-disease}

\textbf{Hosted file}

\verb`COVID-19 Tables IJMP.docx`  available at \url{https://authorea.com/users/469162/articles/562220-using-troponin-i-levels-on-admission-as-a-predictor-of-severity-and-outcome-in-covid-19-virus-disease}

\textbf{Hosted file}

\verb`COVID-19 Figures IJMP.docx`  available at \url{https://authorea.com/users/469162/articles/562220-using-troponin-i-levels-on-admission-as-a-predictor-of-severity-and-outcome-in-covid-19-virus-disease}

\selectlanguage{english}
\FloatBarrier
\end{document}

