3.6 Low EVI1 expression independently predicted poor outcomes
Univariate analysis of RFS and OS in the whole cohort were shown in Table 2. In addition to EVI1 expression at diagnosis, age <1 or >10 and E2A-PBX1 fusion gene were significantly related to lower RFS rate. Furthermore, WBC count ≥30×109/L and E2A-PBX1 fusion gene were significantly related to lower OS rate (all P <0.05).
Variables with P <0.20 in univariate analysis were entered into multivariate analysis. As shown in Table 3, low EVI1 expression, age <1 or >10 and E2A-PBX1 fusion gene were independent adverse prognostic factors for RFS, and low EVI1 expression was the only independent adverse prognostic factor for OS.