3.2 EVI1 expression patterns of the entire cohort
All 176 patients had detectable EVI1 transcript and the median levels
were 0.33% (range, 0.0068-136.2%, Fig. 1A). We previously reported
that the median EVI1 transcript levels in 27 normal bone marrow (NBM)
were 4.5% (range, 2.1-8.0%, Fig. 1A).13 Compared to
EVI1 transcript levels in NBM, pediatric Ph-negative BCP-ALL patients
had significantly lower EVI1 transcript levels (P<0.0001).