INTERLEUKIN 6 AS A MARKER OF SEVERE BACTERIAL INFECTION IN
CHILDREN WITH SICKLE CELL DISEASE AND FEVER
Elena María Rincón-López¹ ², MD; María Luisa Navarro Gómez¹ ³, MD, PhD;
Teresa Hernández-Sampelayo Matos¹ ³, MD, PhD; David Aguilera-Alonso¹,
Eva Dueñas Moreno¹; MD; Jesús Saavedra-Lozano¹ ³ MD, PhD; Begoña
Santiago García¹, MD, PhD; María del Mar Santos Sebastián¹, MD; Marina
García Morín⁴, MD; Cristina Beléndez Bieler⁴, MD; Jorge Lorente Romero⁵,
MD; Elena Cela de Julián³ ⁴, MD, PhD on behalf of F-DREP Study Group*.
*A list of other contributors of the F-DREP Study Group and their
affiliations is provided in the Collaborators section.
Affiliations: ¹Pediatric Infectious Diseases Unit, Hospital
General Universitario Gregorio Marañón, Instituto de Investigación
Sanitaria Gregorio Marañón, Madrid, Spain. ²PhD Program in Medicine,
Universidad Complutense de Madrid, Spain. ³Universidad Complutense de
Madrid, Spain. ⁴Pediatric Hematology and Oncology Unit, Hospital General
Universitario Gregorio Marañón, Madrid, Spain. ⁵Pediatric Emergency
Unit, Hospital General Universitario Gregorio Marañón, Madrid, Spain.
Address correspondence to: Elena M. Rincón-López. Servicio de
Pediatría, Sección Enfermedades Infecciosas, Hospital Materno-Infantil
Gregorio Marañón, c/ O’Donnell, 48-50, 28009 Madrid, Spain. Phone
number: 0034 650060285. E-mail: elenarinconlopez@hotmail.com
Word count: Abstract: 250 words. Main text: 2738 words.
Figures and tables: 2 figures and 4 tables. 1 supplemental
table.
Short title: IL-6 in sickle cell disease.
Key words: Sickle cell disease, infection, fever, cytokines,
interleukin-6.
Data availability: The data that support the findings of this
study are available on request from the corresponding author. The data
are not publicly available due to privacy or ethical restrictions.