Figure 2 |
1H NMR spectra of (A) TNPs, (B) 3TT-IC-4Cl,
and (C) FA-PEG-PBLA10. |
Figure 3 |
(A) TEM image of TNPs, (B) Typical size distributions of TNPs
(insert). |
Figure 4 |
(A) UV–Vis absorption spectra of free 3TT-IC-4Cl (red) and
TNPs (black), and (B) Fluorescence spectra of free 3TT-IC-4Cl (red) and
TNPs (black). |
Figure 5 |
(A) Photothermal conversion behavior of TNPs at different
concentrations (0-250 μg/mL) under 880 nm irradiation at 0.7
W/cm2, (B) Photothermal conversion behavior of TNPs at
different laser power (0.3-1.5 W/cm2) under 880 nm
irradiation at 0.7 W/cm2, and (C) IR thermal images of
TNPs at different concentrations (0-250 μg/mL) under 880 nm irradiation
at 0.7 W/cm2, and (D) IR thermal images of TNPs at
different laser power (0.3-1.5 W/cm2) under 880 nm
irradiation at 0.7 W/cm2. |
Figure 6 |
(A) Temperature elevation of TNPs, and free ICG under five
irradiation/cooling cycles (under 880 nm irradiation at 0.7
W/cm2 for 5 min), (B) Photographs of the TNPs, and
free ICG in PBS solutions after 880 nm light irradiation for different
time. |
Figure 7 |
In vitro cytotoxicity test using
FA-PEG-PBLA10 and TNPs against HeLa cells (A) dark
toxicity depending on the nanoparticles concentration and (B)
phototoxicity depending on nanoparticles concentration. |