LIMITATIONS
Whereas the pacing protocol was intended to mimic focal ATs, the ICPM software was not validated for reentrant arrhythmias. Also, considering these were healthy animals, it is unclear if the reliability of the automated algorithms would be affected by diseased conduction tissue. Finally, because the protocol was carried out in fully anesthetized and intubated swine, there were no undue movements. In a setting of conscious sedation, patient or catheter movements could have an impact on mapping procedures in general.