LIMITATIONS
Whereas the pacing protocol was intended to mimic focal ATs, the ICPM
software was not validated for reentrant arrhythmias. Also, considering
these were healthy animals, it is unclear if the reliability of the
automated algorithms would be affected by diseased conduction tissue.
Finally, because the protocol was carried out in fully anesthetized and
intubated swine, there were no undue movements. In a setting of
conscious sedation, patient or catheter movements could have an impact
on mapping procedures in general.