Introduction
Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) could
infect various organs by different mechanisms (1). This includes the
central nervous system (CNS) and peripheral nervous system (2).
Examination of autopsy tissue from the patients with SARS-CoV-2
infection demonstrated that this virus has the potential to enter the
CNS via attacking the vascular system and damaging the blood-brain
barrier (3). Furthermore, post-mortem examination of patients infected
with COVID-19 has revealed that SARS-CoV-2 could directly target
cortical neurons, which may be associated with immune cell infiltration
in the brain (4-5). Among various neurological manifestations,
the occurrence of seizures during the acute phase of SARS-CoV-2
infection has been reported (5-6). Here, we report a patient with status
epilepticus and a positive SARS-CoV-2 ribonucleic acid test of the
cerebrospinal fluid (CSF).