Abstract
Background : Mucormycosis is a group of life-threatening
diseases caused by a fungus of Mucoraceae family and has a higher
mortality rate compared to other known fungal infections. Hydatid cyst,
caused by Echinococcus, is crucial a health concern in endemic areas and
the disease is characterized by slow-growing cysts in liver, lungs, or
other organs. In this report, a woman with coexistence of hydatid cyst
and Mucormycosis is introduced.
Case Report : The patient was a 52-year-old woman with
approximately 6 years’ history of uncontrolled diabetes mellites and
hypothyroidism, who presented with cough, sputum and dyspnea 2 months
ago. On the initial auscultation of the lungs, there was a decreased
sound at the base of the left lung and she had fever. In blood tests,
she had a high titer of erythrocyte sedimentation rate (ESR) and 3+
C-Reactive Protein (CRP). The symptoms in favor of hydatid cyst were
observed in lung computed tomography and in pleural needle biopsy,
hydatid cyst was confirmed. With this indication, she undergone wedge
resection, resection of the left lower lung cyst. Two samples are taken
from the cyst side and the pathology report was consistent with
Mucormycosis (wide filaments with a 90-degree angle). The patient was
immediately treated with liposomal amphotericin for a 4-week period.
Lung CT scan was performed before and after treatment. Albendazole was
treated in order to treat hydatid cyst. After discharge, the treatment
of the patient continued with oral Posaconazole, and after the treatment
finalization, the general condition of the patient was good and she did
not have any complaints.
Conclusion: In pulmonary diseases that do not respond
significantly to surgical treatment (such as hydatid cyst), fungal
disease (mucor) must be considered simultaneously. Mucormycosis has more
prevalence in patients with uncontrolled diabetes and it is necessary to
be considered if these patients were infected to pneumonia and their
symptoms did not improve with usual treatments.
key words: Mucormycosis, Cyst Hydatid, Lung Infection, Case
Report.