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\begin{document}

\title{Gabapentin utilization among older adults with different cognitive
statuses enrolled in the National Alzheimer's Coordinating Center
(2006-2019)}



\author[1]{GYeon Oh}%
\author[2]{Daniela Moga}%
\author[3]{Erin Abner}%
\affil[1]{University of Kentucky}%
\affil[2]{University of Kentucky, College of Pharmacy}%
\affil[3]{University of Kentucky, College of Public Health}%


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  \date{May 23, 2024}


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\begin{abstract}
This study aimed to examine gabapentin utilization trends among older
adults with different cognitive statuses and investigate concurrent
medication use of potentially inappropriate medications. Data were
extracted from National Alzheimer's Coordinating Center Uniform Data Set
(2006-2019). We estimated the yearly prevalence of gabapentin use, both
overall and within subgroups defined by cognitive status {[}normal, mild
cognitive impairment, and dementia{]} and demographics {[}age and sex{]}
for participants aged 65+. Additionally, we assessed the prevalence of
concurrent use of gabapentin with opioids, combined opioids and
benzodiazepine, antidepressant, and antipsychotic. Participants reported
gabapentin use increased from 2006 to 2019 in both overall and every
participant subgroup. About 10-30\% of gabapentin users reported to
concurrently use of opioids, and more than 50\% gabapentin users with
dementia reported to concurrently use gabapentin with antidepressants.
Given increasing use among older adults, rigorous studies are needed to
examine the safety of gabapentin in this population.%
\end{abstract}%



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