Author contributions
LS, SW, BH and CW contributed ideas. LS, SW, BH and CW designed experiments and interpreted results. BH performed all the experiments. TW, JY, AJ, YL, YL and XD helped with the experiments and manuscript preparation. BH and JY prepared the figures. LS, SW and BH wrote the manuscript. PJW, HC, GD and FX edited the manuscript.