4.2 JAK inhibitors in treating ARDS
Inhibition of JAK kinase may suppress ARDS and pneumonia for JAKs
enrolled in the function and concentrations of pro-inflammatory
cytokines, and JAKs play a vital role in pulmonary physiopathology
especially epithelial cell barrier function. The potential therapeutic
effects of JAK inhibitors in ARDS become revealed as the outbreak of the
COVID related pneumonia and become a new crucial strategy for dealing
with other types of ARDS.