4.2 JAK inhibitors in treating ARDS
Inhibition of JAK kinase may suppress ARDS and pneumonia for JAKs enrolled in the function and concentrations of pro-inflammatory cytokines, and JAKs play a vital role in pulmonary physiopathology especially epithelial cell barrier function. The potential therapeutic effects of JAK inhibitors in ARDS become revealed as the outbreak of the COVID related pneumonia and become a new crucial strategy for dealing with other types of ARDS.