Author contribution
YW, YT and IN were involved in the clinical management. YW wrote the manuscript. IN and HW was involved in the revision of the manuscript. All authors approved the final version for submission.
1. Albibi R, McCallum RW. Metoclopramide: pharmacology and clinical application. Ann Intern Med 98(1):86-95, 1983.
2. Hesketh PJ, Kris MG, Basch E, et al. Antiemetics: ASCO Guideline Update. J Clin Oncol 38(24):2782-2797, 2020.
3. Gan TJ, Belani KG, Bergese S, et al. Fourth Consensus Guidelines for the Management of Postoperative Nausea and Vomiting. Anesth Analg 131(2):411-448, 2020.
4. Tisdale JE, Chung MK, Campbell KB, et al. Drug-Induced Arrhythmias: A Scientific Statement From the American Heart Association. Circulation 142(15):e214-e233, 2020.
5. Drew BJ, Ackerman MJ, Funk M, et al. Prevention of torsade de pointes in hospital settings: a scientific statement from the American Heart Association and the American College of Cardiology Foundation. Circulation 121(8):1047-1060, 2010.
6. Bor S, Demir M, Ozdemir O, Yuksel K. A meta-analysis on the cardiac safety profile of domperidone compared to metoclopramide. United European Gastroenterol J 6(9):1331-1346, 2018.
7. Sarganas G, Garbe E, Klimpel A, Hering RC, Bronder E, Haverkamp W. Epidemiology of symptomatic drug-induced long QT syndrome and Torsade de Pointes in Germany. Europace 16(1):101-108, 2014.
8. Wolfes J, Ellermann C, Burde S, Fehr M, Eckardt L, Frommeyer G. Proarrhythmic potential of metoclopramide in a sensitive whole-heart model. Basic Clin Pharmacol Toxicol 128(6):741-746, 2021.
9. Ellidokuz E, Kaya D. The effect of metoclopramide on QT dynamicity: double-blind, placebo-controlled, cross-over study in healthy male volunteers. Aliment Pharmacol Ther 18(1):151-155, 2003.
10. Chou CC, Wu D. Torsade de pointes induced by metoclopramide in an elderly woman with preexisting complete left bundle branch block. Chang Gung Med J 24(12):805-809, 2001.
11. Siddique SM, Shariff N, Vesuwala N, Hafiz T. Metoclopramide as a possible cause of prolonged QT syndrome and torsade de pointes in a patient with heart failure and renal insufficiency. In: Ann Intern Med. United States, 2009:502-504.
12. Gnanapandithan K, Karthik N, Gerber J. Methadone, Metoclopramide and Metronidazole Interaction Causing Torsades de Pointes. In: Clin Pract. 2021:101-105.