Figure 3. Allicin inhibits hyperproliferation in the keratinocytes. (A) Cell viability of IL-17A-stimulated HaCaT cells treated with different concentrations of allicin was measured by CCK-8 assay (n=6). (B) The cell cycle distribution of PI labeling in different phases with different concentrations of allicin after 48h. (C) Percentages of G0/G1, S, and G2/M-phase cells with different concentrations of allicin after 48h (n=3). (D) Representative immunohistochemical images and the relative expression of Ki67 in IMQ-induced psoriasis-like lesions treated with or without allicin (AH, allicin high-dose). Scale bar = 50 μm. Data are expressed as means ± SD. *p < 0.05, **p < 0.01, ***p < 0.001, ****p < 0.0001.