Figure1. Allicin attenuates symptoms of IMQ-induced psoriasis-like lesions in mice. (A) Treatment scheme in the IMQ-induced mice model. (B) Representative images of IMQ-induced psoriatic symptoms on mice dorsal skin treated with or without allicin for 6 days (AL, allicin low-dose; AM, allicin middle-dose; AH, allicin high-dose; TAE, triamcinolone acetonide and econazole cream). The severity of the IMQ-induced dorsal lesions was evaluated by PASI scores (n=6), and the cumulative scores of redness (C), scale (D), and thickness (E) were measured daily (F). Representative images of H&E staining (G) and respective histopathological scores (H) of IMQ-induced psoriatic lesions in each group (n=3). Scale bar = 50 μm. Data are expressed as means ± SD. *p < 0.05, **p < 0.01, ***p < 0.001, ****p < 0.0001.