Figure 5. RNA-seq reveals the mechanism of allicin ameliorating IMQ-induced psoriasis-like lesions by repressing the IL-17 signal pathway. (A) Volcano plot of downregulated (blue) and upregulated (red) DEGs between allicin treated/untreated IMQ-induced psoriatic lesions. (B) Heatmap of the top 50 downregulated DEGs with or without allicin. (C) KEGG pathway analysis of DEGs (FDR < 0.1). (D) The downregulated DEGs were classified based on their gene ontology (GO) terms for biological process (BP), cellular component (CC), and molecular function (MF).