Figure 2. The comparison of dynamic changes of median WBC count
and median WBC normalized value between ATO and RIF group by risk
stratification.
(A)In NHR group: There were statistically differences in WBC count
between the ATO and RIF group at five time points. They are D0, Day 6-8,
Day 12-14, Day 15-17 and Day 18-20 (p = 0.047, p = 0.034,p = 0.035, p = 0.044 and p = 0.031, separately).
Using mixed linear model to analyze the overall dynamic trend of ATO and
RIF groups, p = 0.004. (B)In HR group: The overall dynamic trend
between ATO and RIF group was compared by mixed linear model, p =
0.404. Using Mann-Whitney U test to compare the WBC count at different
time points, all p value > 0.05 between ATO and RIF
group. (C)In NHR group: Comparison in the dynamic trend of WBC
normalized value between ATO and RIF groups by mixed linear model,p = 0.480. Mann-Whitney U test was used to compare the WBC
normalized value at different time points, p > 0.05.
(D)In HR group: The overall dynamic trend of WBC normalized value was
compared between ATO and RIF, p = 0.379. WBC normalized values at
different time point were compared using Mann-Whitney U test, allp value > 0.05.