Associations between LBBAP and echocardiographic parameters
There was a statistically significant increase in LVEF after LBBAP implantation. There was a mean LVEF difference of 16.38% (95% CI 13.13 to 19.63 I2  = 90.2 %) after the procedure compared with the patient’s baseline, with a marginal difference between the PICM and non-PICM group (12.77% vs. 17.60%, p = 0.07) but not between Chinese versus non-Chinese populations (17.16% vs. 14.97%, p = 0.54). Moreover, significant improvements were also seen in LVESV, LVEDD, LVEDV and LVESD with respective mean differences before and after treatment of −46.23 mL (95% CI −63.17 to −29.29, I2 = 86.82%), −7.21 mm (95% CI −9.71 to −4.71, I2  = 84.6%), −44.52 mL (95% CI −64.40 to −24.64, I2  = 85.9 %) and −12.15 mm (95% CI −14.87 to −9.43,I2 = 38.64%).