Biosynthesis of geranate via isopentenol
utilization pathway in Escherichia
coli
Qiuchi Pan1,2, Xiaoqiang Ma1,2,3,
Hong Liang1,2, Yurou Liu1,2, Gregory
Stephanopoulos1,4,*, Kang Zhou1,2,*
1. Disruptive & Sustainable Technologies for Agricultural Precision
(DiSTAP), Singapore-MIT Alliance for Research and Technology, Singapore
2. Department of Chemical and Biomolecular Engineering, National
University of Singapore, Singapore
3. Department of Food Science and Technology, School of Agriculture and
Biology, Shanghai Jiao Tong University, Shanghai, China
4. Department of Chemical Engineering, Massachusetts Institute of
Technology, Cambridge, United States
*Corresponding authors: Kang Zhou
(kang.zhou@nus.edu.sg)
and Gregory Stephanopoulos
(gregstep@mit.edu)
Key words: isopentenol utilization pathway, isoprenoids, geranate,
pathway engineering, metabolic engineering