3.2 Comparison of Oncology Outcomes Between the total study
population and 1:4 PSM in the early FIGO2018 stage oflaparotomy group and
laparoscopy group
In the total study population, K-M survival analysis showed that there
was no significant difference in the 5-year OS between the laparotomy
group and laparoscopy group (96.2% vs. 96.0%, P = 0.989) (Table 2 and
figure 2A).The 5-year DFS in laparotomy group was higher than that in
laparoscopy group (92.2% vs. 90.4%, P = 0.022). (Table 2 and figure
2B).Cox analysis showed that laparoscopic surgery was not an independent
risk factor for death in patients with cervical squamous cell carcinoma
(OS: P = 0.598), but it was an independent risk factor for recurrence /
death in patients with cervical squamous cell carcinoma (HR = 1.468,
95% CI 1.131 ~ 1.906, P = 0.004).(Table 2).
The results of K-M survival analysis after 1:2 PSM showed that there was
no significant difference in 5-year OS between the laparotomy group
(2391 cases) and laparoscopy group (1495 cases) (96.5% vs. 96.0%, P =
0.684). (Table 2 and figure 2C). The 5-year DFS in laparotomy group was
higher than that in laparoscopy group (92.7% vs. 90.8%, P = 0.006).
See Table 2 and figure 2D. Cox multivariate analysis showed that
laparoscopic surgery was not an independent risk factor for death in
patients with cervical squamous cell carcinoma (OS: P = 0.521), but it
was an independent risk factor for recurrence / death in patients with
cervical squamous cell carcinoma (HR = 1.512, 95% CI 1.151
~ 1.971, P = 0.002).(Table 2).