Patients
Between August 2016 and June 2023, 85 children diagnosed with AA who
underwent allogeneic HSCT were included in this study. The patients were
treated at the pediatric stem cell transplantation unit of Wuhan
Children’s Hospital. ABO compatibility was documented in 38
donor–recipient pairs, while ABO incompatibility was documented in 47
pairs (17 major, 21 minor, 9 bi-directional).
The protocol of this clinical observation study adhered to the tenets of
the Declaration of Helsinki and received approval from the Wuhan
Children’s Hospital Ethics Committee (approval no. 2022R071-E01).
Written informed consent was obtained from all patients in accordance
with the principles of the Declaration of Helsinki.