Induction of systemic, mucosal and cellular immunity against
SARS-CoV-2 in mice intratracheally vaccinated with a viral S1 protein
combined with a pulmonary surfactant-derived adjuvant SF-10
Takashi Kimotoa, ¶, Satoko
Sakaia, b, c ¶, Keiko
Kamedaa, Ryoko Moritaa, Etsuhisa
Takahashia, Yasuo Shinoharab, c,
Hiroshi Kidoa *
a Division of Enzyme Chemistry, Institute for Enzyme
Research, Tokushima University, Tokushima, Japan
b Faculty of Pharmaceutical Sciences, Tokushima
University, Tokushima, Japan
c Institute for Genome Research, Tokushima University,
Tokushima, Japan
¶ These two authors contributed equally to
this work.
* Correspondence : Hiroshi Kido,
Division of Enzyme Chemistry, Institute for Enzyme Research, Tokushima
University, Tokushima 770-8503, Japan.
Fax: +81 88 633 7425, Tel: +81 88 633 7423,
(kido@tokushima-u.ac.jp)
Running head : Intratracheal SARS-CoV-2-SF-10 vaccination in mice