Induction of systemic, mucosal and cellular immunity against SARS-CoV-2 in mice intratracheally vaccinated with a viral S1 protein combined with a pulmonary surfactant-derived adjuvant SF-10
Takashi Kimotoa,, Satoko Sakaia, b, c ¶, Keiko Kamedaa, Ryoko Moritaa, Etsuhisa Takahashia, Yasuo Shinoharab, c, Hiroshi Kidoa *
a Division of Enzyme Chemistry, Institute for Enzyme Research, Tokushima University, Tokushima, Japan
b Faculty of Pharmaceutical Sciences, Tokushima University, Tokushima, Japan
c Institute for Genome Research, Tokushima University, Tokushima, Japan
These two authors contributed equally to this work.
* Correspondence : Hiroshi Kido, Division of Enzyme Chemistry, Institute for Enzyme Research, Tokushima University, Tokushima 770-8503, Japan.
Fax: +81 88 633 7425, Tel: +81 88 633 7423, (kido@tokushima-u.ac.jp)
Running head : Intratracheal SARS-CoV-2-SF-10 vaccination in mice